GNW-Adhoc: Continued good Cresemba® (isavuconazole) sales in the Asia-Pacific region and China trigger third milestone payment from Pfizer this year for…

^Allschwil, November 20, 2023

Basilea Pharmaceutica AG, Allschwil (SIX: BSLN), a biopharmaceutical

Companies with already marketed products and the goal of reaching patients

help those suffering from serious bacterial or fungal infections,

announced today that sales of the antifungal drug continue to be strong

Cresemba® (isavuconazole) through Basilea’s licensing partner Pfizer Inc. (NYSE: PFE,

“Pfizer”) exceeded the threshold in the Asia-Pacific and China region

which will result in an additional sales milestone payment of USD 1.25 million.

was triggered.

David Veitch, Chief Executive Officer of Basilea, said: “This is the third

Milestone payment relating to sales in the Asia-Pacific and China regions

this year. This underlines that Cresemba continues to have a high

medical needs also cover and reflect the significant commercial ones

potential of the product in this region. We are pleased that Cresemba

is well on its way to becoming a world-leading drug for the treatment of

To become patients with invasive mold infections.”

The license agreement between Basilea and Pfizer covers Europe (excluding

Nordic countries), as well as 16 countries in the Asia-Pacific region and China.

Cresemba is approved in 76 countries and is currently marketed in 71 countries,

including the USA, most EU member states and other countries

within and outside Europe. According to the latest available market data

Cresemba’s global in-market sales amounted to

Twelve-month period between July 2022 and June 2023 to USD 421 million

corresponds to growth of 19 percent compared to the same period last year.(1)

About isavuconazole (Cresemba(®))

Isavuconazole is a medicine that can be administered intravenously (IV) and orally

against fungal infections (antimycotic) from the active ingredient class of azoles, which

marketed under the trade name Cresemba(®). Basilea has for isavuconazole

License and sales partnerships for a total of around 115 countries

completed. In the 27 member states of the European Union as well

Great Britain, Iceland, Liechtenstein and Norway isavuconazole is for the

Approved for treatment of adult patients with invasive aspergillosis and

for adult patients with mucormycosis, for whom amphotericin B is not

is appropriate.(2) In China, the oral and the intravenous

Dosage forms for the treatment of adult patients with invasive

Aspergillosis and invasive mucormycosis approved. Isavuconazole is also in the

Approved in the USA and other countries within and outside of Europe,

including Japan.(3)In the USA, Europe and Australia, Cresemba has orphan drug approval

Status for the approved indications.

About Basilea

Basilea is a company founded in 2000 with headquarters in Switzerland

biopharmaceutical company with already marketed products. Our goal

is to discover, develop and market innovative medicines

To help patients suffering from serious bacterial or fungal infections

are sick. With Cresemba and Zevtera we have two successful drugs

brought onto the market for use in hospitals: Cresemba for the treatment of

invasive fungal infections and Zevtera to treat bacterial infections.

We also have a portfolio of preclinical and clinical products

Anti-infective programs. Basilea is listed on the Swiss stock exchange SIX Swiss Exchange

listed (stock exchange symbol SIX: BSLN). Please visit our website basilea.com

(https://www.basilea.com/).

Disclaimer

This communication contains, expressly or implicitly, certain forward-looking statements

Statements such as “believe,” “assume,” “expect,” “predict,” “plan,”

“May”, “could”, “will” or similar expressions regarding Basilea

Pharmaceutica AG, Allschwil and its business activities, including in relation to

the progress, schedule and completion of research and development

as well as clinical studies with product candidates. Such statements include

known and unknown risks and uncertainty factors that result

can that the actual results, the financial situation, the achievements

or achievements of Basilea Pharmaceutica AG, Allschwil significantly from

The information contained in the forward-looking statements may differ

emerge. This notice is dated today. Basilea

Pharmaceutica AG, Allschwil assumes no obligation,

forward-looking statements in the event of new information, future

events or for other reasons.

For further information please contact:

Peer Nils Schröder, PhD

Head of Corporate Communications & Investor Relations

Basilea Pharmaceutica AG, Allschwil

Hegenheimermattweg 167b

4123 Allschwil

Switzerland

Telephone +41 61 606 1102

[email protected] (mailto:[email protected])

Email [email protected] (mailto:[email protected])

This press release is at www.basilea.com

(http://www.basilea.com) available.

Sources

1. IQVIA Analytics Link, June 2023. Information as moving, cumulative «in-

Market» sales of the last twelve months in US dollars.

2. European Public Assessment Report (EPAR) Cresemba: http://www.ema.europa.eu

(http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-

_Summary_for_the_public/human/002734/WC500196131.pdf) [Zugriff am 19.

November 2023]

3. The approval status and approved indications may vary from country to country

Country may be different.

°

ttn-28