Thiago gave the visitors the lead in the eighteenth minute. He tapped in from close range after good preparatory work by Skov Olsen. At that moment, debutant Daniel Schmidt was already between the posts at Ghent. Davy Roef had recently dropped out with a muscle injury.
On the other side, Simon Mignolet had to show his ability just before the half hour on an attempt by Hugo Cuypers.
After the break, Ghent had to look for the equalizer, but just like in the first half, the chances were scarce. The Buffaloes had more ball possession, but had difficulty converting that into real danger in front of goal, until the final phase.
Gift Orban had an excellent opportunity in the 75th minute, but the attacker struck the Bruges goalie face to face with Mignolet. A shot by Samoise was cleared just before the line by Spileers in extra time.
Club Brugge will meet Union or Anderlecht in the last four. The winners of OH Leuven-Antwerp and Oostende-RWDM will play the other semi-final battle. This will be completed in back and forth matches. The semi-final matches will take place on January 23, 24 or 25 (first) and February 27, 28 and 29 (return). The final will be played on Thursday, May 9.