Non the panorama of contemporary medicine, few practices have been able to evolve with the constancy ofoxygen-ozone therapytransforming from an empirical practice to a clinical treatment. Writing about this method today means immersing yourself in a fascinating mechanism of “positive stress”, capable of reawakening the body’s natural defenses without resorting exclusively to pharmacological synthesis.
Understanding this process, which however requires clinical experience to distinguish what is biologically rational from what is demonstrated benefit, means discovering how a natural element can become a precious ally for daily health and vitality.
A medicine that communicates with the body
There is a medicine that does not promise miracles, but works in depth. It doesn’t replace the body, it stimulates it. It doesn’t turn off the signals, it interprets them. It is theoxygen-ozone therapya practice that over the years has made a discreet but solid journey, moving from an empirical approach to clinical treatment supported by scientific evidence.
Telling it today means entering the heart of a fascinating concept: that of positive stresscapable of reawakening the body’s natural defenses without resorting exclusively to pharmacological synthesis. A dialogue with biology, more than an imposition.
Hormesis: when stimulus becomes force
From a biological point of view, the mechanism is refined. Ozone works throughhormesis: when the gaseous mixture comes into contact with the blood or tissues, it induces a production transient and controlled rate of reactive oxygen species. Not damage, but a signal.
This stimulus activates a virtuous response: the organism increases the production of protective enzymes such as superoxide dismutase and catalase. It’s a real one cellular trainingwhich makes tissues more resilient and prepared to face daily stress.
Microcirculation and oxygenation: energy for tired tissues
The action of ozone also extends to microcirculationimproving the deformability of red blood cells. A crucial aspect, because it allows for more efficient transport of oxygen and nutrients even in the smaller and tired capillariesoften responsible for pain and functional slowdowns.
Spine: the scientific evidence
One of the most studied areas is that of spinal pathologies. Meta-analyses published in international journals confirm that oxygen-ozone infiltrations reduce inflammation related to herniated disc and promote the dehydration of the expelled material, decreasing nerve compression. The result is one pain reduction and documented functional improvement.
Chronic fatigue and post-viral syndromes
Research also shows promising applications in the use of Large Autohemotransfusion (GAE) for the management of chronic fatigue and of post-viral syndromes. Preliminary clinical studies indicate that ozone works by modulating the immune system and reducing pro-inflammatory cytokines such as IL-6 and TNF-α, with evident benefits on energy levels and on quality of sleep.
Vascular well-being: light legs
In the vascular field, scientific evidence also shows benefits invenous insufficiency. The increase in oxygen delivery to the tissues, mediated by 2,3-DPGand action anti-platelet aggregator They allow you to effectively counteract heaviness and swelling in the legs, improving daily comfort.
A choice that speaks the language of biology
Turning to oxygen-ozone therapy means choosing a treatment path that respects and stimulates natural biological mechanisms. An approach that requires clinical expertise to distinguish what is rational biological from what is demonstrated benefit, but which, if correctly applied, transforms scientific research into deep and lasting well-being.
The authors
Michele Bonaccorso
Doctor Michele Bonaccorso.
The Dr. Michele Bonaccorso He is a surgeon, specialized in anesthesia and resuscitation, oxygen-ozone therapy and functional medicine.
His virtuous course of study has allowed him to be today among the most qualified exponents of functional medicinewith particular reference tooxygen-ozone therapy and to pain therapy.
He graduated with honors from LUniversity of Catania. For over 10 years he has successfully practiced oxygen-ozone therapy for the treatment of musculoskeletal pathologies, in the treatment of neurodegenerative and inflammatory diseasesand as a technique prevention and slowing down of aging.
He attended anti-aging medicine school AMIA (Italian Antiaging Doctors Association) directed by Dr. Galimberti. He graduated from the school ofAIMF HEALTH (Italian Association of Functional Medicine) which allowed him to become functionalist doctor. Finally, he obtained a II level Master’s degree in Pain Therapy from the University of Parma. He served as the group’s pain therapy manager Multimedical. He follows national and international conferences with interest which allow him to always stay up to date on the latest news in the field of functional medicine and anti-aging.
Doctor Nicola Marino
The Dr. Nicola Marino carries out research activities with the Swiss group Women’s Brain Foundationfor which he is a member of the advisory board, in the fields of longevity and artificial intelligence. Director of AEON Foundation and former political consultant in the field of digital health and longevity, he is the author of numerous scientific publications.
He carried out an internship at the Harvard Medical School and the Dana-Farber Cancer Institute of Bostonwas a member of Scientific Committee of the Italian Association of Digital Health and Telemedicine (AISDET) and consultant for the US company Health Catalyst. He carries out scientific journalism activities for national and international media, and has been involved as an expert for CFI.co, Il Sole 24 Ore, Corriere della Sera, Millionaire, Rai1 and Sky TG24, to name a few.