The New York-based Duquesne Family Office of the legendary star investor Stanley Druckenmiller shook up its US stock portfolio in the first quarter of 2026.
Star investor Stanley Druckenmiller recently managed investments worth around $3.38 billion through his Duquesne Family Office (as of March 31, 2026). Since the assets under management are well above the reporting threshold of $100 million, he must file a 13F form with the US Securities and Exchange Commission quarterly, disclosing his investments.
In the first quarter, Druckenmiller proved extremely lucky with his absolute favorite stock, which he massively increased again despite an already gigantic weighting. At the same time, he used the first months of the year to catch up spectacularly in the energy sector and put a big exclamation mark on a South American recovery story, while some former tech and biotech heavyweights lost ground in the rankings.
The following ranking shows the star investor’s ten largest shareholdings according to their share of the total portfolio as of March 31, 2026. Investments in other forms of investment such as ETFs were not taken into account.
Alexandra Hesse, editorial team at finanzen.net
11th place: The ranking
Star investor Stanley Druckenmiller manages a billion-dollar stock portfolio through his Duquesne Family Office. As of March 31, 2026, the total value of its holdings was around $3.38 billion. Since the portfolio is well above the threshold of 100 million US dollars, Druckenmiller is obliged to submit a 13F form to the US Securities and Exchange Commission (SEC) every quarter in which he discloses his investments.
The following ranking lists the ten largest stock holdings of the Duquesne Family Office in the first quarter of 2026, sorted by their share of the total portfolio. Investments in other forms of investment such as ETFs were not taken into account. The basis is the status at the end of the quarter on March 31, 2026.
Source: sec.gov, Image: TunedIn by Westend61 / Shutterstock.com
10th place: Woodward
The manufacturer of control systems and components, Woodward, slipped directly into the top 10 pure equity stocks by excluding fund structures. Druckenmiller sold 379,575 shares in the first quarter, which corresponded to a significant decrease of 64.23 percent. The remaining 211,355 shares secured a portfolio weight of 2.24 percent with a rounded market value of $75.65 million.
Source: sec.gov, Image: MacroEcon / Shutterstock.com
9th place: STMicroelectronics
The European semiconductor manufacturer STMicroelectronics secured its entry into the top 10 through an aggressive wave of purchases. Druckenmiller expanded the position in the first quarter by a whopping 1,839,325 ADR shares traded in the USA – a huge increase of 237.78 percent. The holdings thus grew to 2,612,880 shares, which had a market value of $90.28 million at the end of the quarter (2.67 percent of the portfolio).
Source: sec.gov, Image: Pavel Kapysh / Shutterstock.com
8th place: Sea
The Southeast Asian technology company Sea claimed a portfolio share of 2.70 percent as of the reporting date. The family office increased its commitment by 155,785 shares (+16.50 percent) in the reporting period. The total package of 1,099,905 shares had a rounded market value of $91.08 million at the end of the quarter.
Source: sec.gov, Image: Wirestock Creators / Shutterstock.com
7th place: NewAmsterdam Pharma Company
The picture remained unchanged for the biotech company NewAmsterdam Pharma Company, which accounted for 2.91 percent of the US portfolio. Druckenmiller did not touch the position in the first three months of the year and held on to his 3,070,146 papers. The value of the shares was around $98.28 million at the end of the quarter.
Source: sec.gov, Image: Adam Michal Ziaja / Shutterstock.com
6th place: Alcoa
The US aluminum company Alcoa posted a market value of $99.06 million at the end of the quarter. After investing in the previous quarter, the family office purchased a further 117,340 shares in the first quarter (+8.53 percent). The 1,493,390 shares held accounted for 2.93 percent of the portfolio as of the reporting date.
Source: sec.gov, Image: Alcoa
5th place: BBB Foods
The Mexican chain BBB Foods took fifth place. Druckenmiller expanded the investment by 434,050 shares in the first quarter (+16.23 percent) and held a total of 3,109,202 shares as of the reporting date. At the end of the quarter, these recorded a rounded market value of $109.97 million, which made up 3.26 percent of the portfolio.
Source: sec.gov, Image: rblfmr / Shutterstock.com
4th place: YPF
The absolute high-flyer in the first quarter was the Argentine oil and gas company YPF. Druckenmiller ignited the turbo here and increased the position by a phenomenal 2,628,972 shares traded in the USA – an increase of 433.12 percent. The package, which now includes 3,235,962 shares, had an impressive market value of $149.57 million as of the reporting date and captured a portfolio share of 4.43 percent.
Source: sec.gov, Image: Michael Berlfein / Shutterstock.com
3rd place: TSMC
With a weight of 4.96 percent in the total portfolio, the world’s largest chip contract manufacturer TSMC made it onto the podium. The Duquesne Family Office used the quarter for partial profits and sold 47,805 of the ADS securities traded in the USA (-8.80 percent). The remaining 495,280 shares were still worth a significant $167.38 million as of the reporting date.
Source: sec.gov, Image: Michael Vi / Shutterstock.com
2nd place: Insmed
Biotech heavyweight Insmed secured the silver medal with a market value of $188.72 million. However, Druckenmiller noticeably pulled out the red pencil in the first quarter and sold 327,662 shares (-22.11 percent). The remaining 1,154,090 shares in the portfolio corresponded to a portfolio share of 5.59 percent.
Source: sec.gov, Image: JHVEPhoto / Shutterstock.com
1st place: Natera
Natera remained the undisputed, lonely and absolutely gigantic number one in Stanley Druckenmiller’s empire. The star investor was firmly convinced of the potential of the specialist for cell-free DNA tests and bought a further 552,249 shares (+21.99 percent). With 3,063,606 shares now held, the position reached an astronomical market value of $612.69 million, which corresponded to a huge portfolio share of 18.14 percent.
Source: sec.gov, Image: Piotr Swat / Shutterstock.com
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Image sources: TunedIn by Westend61 / Shutterstock.com, Maxx-Studio / Shutterstock.com