Gdear doctor, The same thing has always happened to me for some time: around 3pm I have a sudden collapse. I feel very tired, I struggle to concentrate, I often want something sweet and I struggle to concentrate on work. I seem to get enough sleep and eat lunch regularly. What could it depend on?

Cortisol Jump and stress hormones

What you describe is very common and, in most cases, it is not laziness or lack of willpower.
It is a normal response of the body, linked to the functioning of the nervous system and stress hormones. In the early afternoon, around 2–4 pm, cortisol, the hormone that helps us stay alert and reactive, physiologically drops. Under normal conditions we don’t notice it.
The problem arises when the morning was very intense: continuous stress, multitasking, few breaks, high mental load. In this case the nervous system arrives in the early afternoon already “under pressure”.

Symptoms of Cortisol Jump

When cortisol drops, the body struggles to keep blood sugar stable. The brain interprets this passage as a signal of “low energy” and what is now called may appear cortisol jump: a mini-crash of the autonomic nervous system, characterized by sudden tiredness, difficulty concentrating, urgent cravings for sugar and slight internal agitation.

It’s not “normal” tiredness

It is not “normal” tiredness: it is the signal that the stress regulation system (the hypothalamic-pituitary-adrenal axis) is losing flexibility, as described for years by McEwen). The good news is that this mechanism is modulatable. Small targeted measures are often enough:

  1. a short, slow, diaphragmatic breathing pause to calm the nervous system every hour and a half during the morning
  2. for breakfast a combination of proteins and fibers to stabilize blood sugar during the morning
  3. a few minutes of natural light or a short walk immediately after lunch
  4. avoid, if possible, the maximum cognitive load in that time slot. In summary: the 3pm collapse is not a personal defect, but a message from the body.
    Learning to read it and respond in the right way can make the difference between an afternoon spent “dragging” and one in which energy and clarity gradually return.

Doctor Federica Almondo

Doctor Federica Almondo.

Specialist in Food Science, trained at Dietology and Obesity Center of the San Raffaele Hospital in Milanthe Doctor Federica Almondo it is a point of reference in personalized nutrition, preventive medicine and anti-aging pathways.

After founding and directing Cerva 16 – Nutrition & Anti-aging Center, he created a STUDIO ALMONDO – NUTRITION & LONGEVITYa place where science, technology and a human approach meet to create tailor-made programs. It deals with tools such as genetic tests (DNA), assessments of the state of the intestinal microbiota, analysis of oxidative stress, body composition, indirect calorimetry. But also ANS Analysiss to build highly personalized diets with approach holistic and scientifically validatedsuitable for even the most complex needs.

With excellent training and skills ranging from nutrigenetics and nutrigenomics to nutraceutics, metabolomics and epigeneticsAlmondo is also recognized for her work on intestinal health, menopause, chronic stress management and optimization of psycho-physical energy. Particular attention to ketogenic therapya nutritional approach now totally validated by scientific literature such as effective intervention in many complex pathologiesincluding type 2 diabetes, PCOS, fibromyalgia and lipedema and much more.
Here is his answer to the question.

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