^NEW YORK, Oct. 09, 2025 (GLOBE NEWSWIRE) — Nilo Therapeutics, a

Biotechnology company that uses neural circuits to

Restoring immune homeostasis in diseases started today with a

$101M Series A Funding Led by The Column

Group (TCG), DCVC Bio and Lux ​​Capital, with participation from the Gates Foundation

and Alexandria Venture Investments. At the same time as the market launch, Nilo

the appointment of Dr. Kim Seth as Chief Executive Officer and Board Member

announced.

Nilo was founded by the world’s leading scientists Dr. Charles Zuker

(Columbia University), Dr. Ruslan Medzhitov (Yale University) and Dr. Steve

Liberles (Harvard University) was founded in collaboration with TCG,

to bring groundbreaking scientific findings in neuroimmunology into new ones

implement therapeutic strategies. Dr. Seth will be with Chief

Scientific Officer Dr. Laurens Kruidenier the transformation of the company

guiding a stealth company into the next phase of growth. The financing

is used to set up Nilo’s laboratories in New York City and expand his

interdisciplinary research and development teams and further development

the company’s preclinical programs.

Nilo is developing drugs that use neural circuits to…

Centrally restore immune homeostasis. The company thus offers one

differentiated approach to immune modulation that goes beyond the traditional

Immunosuppression goes beyond. The company is based on groundbreaking

scientific discoveries from the laboratory of Dr. Charles Zuker

(Principal investigator at Columbia University and investigator at Howard Hughes Medical

Institute) who has identified certain vagal neurons that

regulate systemic immune activation and inflammation. Through the targeted

Influencing these central “master-regulator” circuits between the brain and

body, Nilo uses its novel therapeutic approach to target multiple immune pathways

to modulate at the same time, thereby reducing the risk of resistance to therapy

reduced and the potential effect on a broad spectrum of autoimmune

and inflammatory diseases with major unmet needs.

Dr. Seth has over 25 years of experience in the biopharma industry and

has held various leadership positions at several start-ups and

listed biotech companies and large pharmaceutical companies. He has

also comprehensive specialist knowledge in the areas of company structure and strategy

and R&D activities, business development, finance and capital markets. Before

During his time at Nilo, Dr. Seth as Chief Business Officer at Repare

Therapeutics, a precision oncology company. There

He was a member of the management team and played a key role in this

Companies from the pre-Series A financing round to the Series B

Scaling the financing round up to the IPO. He was for construction

of the company’s US business and led the

Business development to deliver across a range of global platforms, assets and

clinical partnerships have secured over $250 million in financing

generate a potential total value of over USD 4 billion.

Before working at Repare, Dr. Seth leadership positions in the

areas of business development, strategy and operations across a range of

biopharmaceutical companies, including Pfizer, and was a research analyst for large-scale

Cap pharmaceutical company/specialty pharmaceutical company at Goldman Sachs. He acquired

his BA cum laude in economics from Harvard College and his

PhD in Neurobiology in the Department of Medical Sciences at the

Harvard University.

Dr. Seth joins Dr. Laurens Kruidenier, Chief Scientific Officer, one

experienced experts in immunology and drug research. Dr.

Kruidenier previously served as CSO at Cellarity and Prometheus Biosciences (from Merck

taken over), where he developed several innovative therapies for autoimmune and

Advancing inflammatory diseases from concept to clinical application. To

Beginning his career at Takeda Pharmaceuticals and GSK, he led teams for

preclinical and discovery research and the strategy for

Business development. He received his doctorate in immunology from Leiden University

and his research results have been published in leading scientific publications

Published in specialist journals, including Nature.

“Nilo is in a phase of change,” says Dr. Laurens Kruidenier,

Chief Scientific Officer of Nilo Therapeutics.?The leadership qualities and

Experience of Dr. Seth will accelerate our mission, groundbreaking

Translating findings from neuroimmunology into medications

Patients with a variety of immune-related diseases benefit

could.”

“We are very pleased, Dr. “To be able to welcome Seth as CEO,” said Dr. Tim Kutzkey,

Managing Partner at The Column Group.?With his track record at

Supporting companies from their beginnings to their IPO and the

Successful implementation of programs brings Dr. Seth both foresight and

visions with. His passion, groundbreaking scientific findings

into innovative medicines makes him the ideal partner to help Laurens’

scientific leadership role and Nilo into the next one

to lead to a growth phase.”

“It is an honor to be part of the incredibly talented and dedicated team

of Nilo,” said Kim Seth, Chief Executive Officer of Nilo Therapeutics.

?Together with Laurens, our world-class scientific founders, and

For our investors, we are building a company that will inspire a new generation

Therapies will be developed that utilize the brain-immune axis to provide treatment

of autoimmune and inflammatory diseases.”

About Nilo Therapeutics

Nilo Therapeutics is a biotechnology company that is creating a new class of

Drugs are being developed that use neural circuits to…

To restore immune homeostasis in diseases. Through the targeted

Influencing the master regulatory circuits between the brain and body, the

To centrally control systemic inflammation, Nilo is doing pioneering work

differentiated approach to immunomodulation that has the potential to be broad

Spectrum of autoimmune and inflammatory diseases with major unmet needs

to treat. The company is headquartered in New York,

NY. www.nilotx.com (https://www.nilotx.com/)

For more information, contact [email protected]

(mailto:[email protected]).

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