A study traced a connection between infertility and an intestinal microbiota

Riccardo Cristilli

May 10 – 11:55 – MILAN

In the world about 186 million people suffer from infertilitya condition that does not have an impact only on the life of a couple but also on the future of the different nations and the whole world. Many infertility factors are still little known and explored, as Linda Vingozzi explained which deals with Andrology and Medicine of Sexuality. This despite about two out of five couples are affected by the problem.

Research on intestine and fertility

The study of the intestinal microbiotathe largest and most complex set of bacteria, viruses and mushrooms of our body, is becoming central in the research related to the theme of fertility. An imbalance inside the microbiota can be crucial in the onset of infertility. A recent study published on Scientific Reports and carried out by the researchers of theUniversity of Beijing He highlighted the possible connection between the intestine and fertility. Through genetic data in evaluating the composition of the intestinal microbiota, the researchers identified 15 groups of bacteria allied bacteria of fertility and 2 enemy strains of reproductive capacity.

The microbiota for fertility

As highlighted in a recent congress of the SIAMS – Italian Society of Andrology and Medicine of Sexualitythis discovery could offer new ideas in early diagnosis, in the prevention and treatment of infertility. So far, in fact, there was no analysis capable of identifying a causal link between microbiota and infertility, above all because other factors, such as lifestyle and diet, ended up interfering in the analysis. Precisely for this reason the research has based on genetic data that cannot be influenced.

the data

The study analyzed information on the genome associated with the microbiota deriving from samples collected on 18 thousand people of several countries including US, South Korea and Germany, age between 50 and 62 years. In men they have been identified 5 groups of bacteria that have a protective effect, including the Bacteroidaceae groups and Enterobacteriales such as the Esserichia coli. There presence of the bacteria of the Allisonella genrehas been connected to the onset of infertility, as promoting oxidative stress, they favor an inflammatory micro -environment that can damage the sperm DNA. In women on 11 bacterial groups Only one showed a negative influence on fertility. This study still has great potential in the analysis of infertility and could change care, opening the way to new therapeutic strategies for Improve the fertility of both sexes.



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