Facing Argentinian Juan Manuel Cerundolo on the 5th day of the tournament held in Paris, the capital of France, Sinner had to take a medical break due to cramps while leading 6-3, 6-2 and 5-1 in sets against his opponent.
While the Italian racket could be heard from the microphones on the court expressing that he was dizzy and nauseous, Sinner lost the third set 7-5 with the points he lost before and after the break.
Cerundolo won the fourth and fifth sets 6-1 against Sinner, whose illness continued, and advanced to the third round.
24-year-old Sinner, who won the championship in Madrid, Monte Carlo and Rome during the clay season and made history as the first athlete to win 6 Masters 1000 tournaments in a row, was seen as the favorite for the championship in the absence of Spanish Crlos Alcaraz.

