^BOSTON, May 28, 2026 (GLOBE NEWSWIRE) — Fortis Life Sciences today announces the
Introducing the AbNano (https://www.fortislife.com/products/anti-nk-cell-vhh-
library)(®) (https://www.fortislife.com/products/anti-nk-cell-vhh-library) VHH
Anti-NK cell library (https://www.fortislife.com/products/anti-nk-cell-vhh-
library), a first-class repertoire of peripheral natural materials
Single domain antibodies (VHH) obtained from killer cells (NK cells).
translational and therapeutic applications related to complex NK
Target receptor systems. The identification and development of antibodies in
NK cell systems are heterogeneous due to the complexity of the receptors
Expression patterns and the dynamic functional states are a technical one
challenge.
Natural killer cells are advancing in cancer immunotherapy and research
Immune-mediated diseases are increasingly coming into focus because they are a central
play a role in immune surveillance and have great potential for the
Next generation cell manipulation and biological strategies
offer. Compact VHH domains may have advantages in conformational or heavy
provide accessible NK-associated target molecules that are suitable for conventional
Antibody formats are problematic.
The AbNano VHH anti-NK cell library addresses these challenges
a natural repertoire tailored to the biology of NK cells
obtained single domain antibodies. The library made from organic
relevant starting material of peripheral NK cells and with regard to them
broad sequence and structural diversity has been characterized, offers academic
and biopharmaceutical teams a differentiated starting point for the
Identification of binding sites, the evaluation of target molecules, the assay
Development and downstream technical workflows.
Internal validation studies identified binding sites on several NK
associated target molecules, including CD56
(https://www.fortislife.com/products/primary-antibodies/rabbit-anti-ncam-1-cd56-
recombinant-monoclonal-antibody-blr152j/BETHYL-A700-152), CD8a
(https://www.fortislife.com/products/primary-antibodies/rabbit-anti-cd8-alpha-
recombinant-monoclonal-antibody-blr044f/BETHYL-A700-044) and NKp46
(https://www.fortislife.com/products/primary-antibodies/rabbit-anti-ncr1-nkp46-
recombinant-monoclonal-antibody-blr309m/BETHYL-A700-309), which is used in
Target molecules with different biological functions and
underpinned by expression patterns.
?NK-associated receptor systems can be identified using conventional research approaches
“Inherently difficult to study,” said Chris Woodward, senior director for
Antibody solutions at Fortis Life Sciences.?Specialized repertoires that
based on biologically relevant source material, researchers and
Helping therapeutics developers create binding molecules against immune targets
to efficiently identify what may be the development of targeted
Immune cell therapies and biologics for cancers and complex
could accelerate immune diseases.”
The launch is the third addition to the growing AbNano(®) range
Portfolios. Similar to other AbNano libraries
(https://www.fortislife.com/products/libraries) it is independent
research product or as part of tailor-made VHH
Discovery Services (https://www.fortislife.com/vhh-discovery)
available, the development of screening strategies, the selection using
Phage display, sequencing analyses, hit triage, conversion
into recombinant formats as well as support in early stages
Include lead substance development.
For more information, visit fortislife.com/products/anti-nk-cell-vhh-
library (https://www.fortislife.com/products/anti-nk-cell-vhh-library)
About Fortis Life Sciences
The company Fortis Life Sciences was founded in 2020
(https://www.fortislife.com/) brings together specialized life science companies
such as Abcore, Arista Biologicals, Bethyl Laboratories, Empirical Bioscience, IPOC,
nanoComposix and Vector Biolabs to help companies lead the way
from research to market launch faster, more continuously and
to proceed in a more controlled manner. By providing high quality products,
tailored services and in-depth technical expertise
Fortis supports its partners in development, validation and
Producing proprietary solutions for complex scientific and
operational requirements. Fortis serves companies worldwide through a
ever-growing global presence, including several cGMP compliant
Production facilities include ISO 13485 certified. More
Information can be found at fortislife.com.
Press contact:
Nick Bartosik
Marketing Specialist
Fortis Life Sciences
[email protected] (mailto:[email protected])
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