GNW-Adhoc: Santhera publishes annual report 2022

^Ad hoc notification pursuant to Art. 53 LR

Pratteln, Switzerland, May 31, 2023 – Santhera Pharmaceuticals (SIX: SANN) announces the

Release of the 2022 annual report with the fully audited

Announced results for the year ended December 31, 2022.

The annual report 2022 provides comprehensive and detailed information about this

company, the strategy, the course of business, the financial performance,

corporate governance and compensation in 2022 and confirms that

Preliminary, unaudited 2022 annual results published on April 27, 2023

became. The annual report 2022 (English) is available on the company’s website

at www.santhera.de/financial-reports (http://www.santhera.de/financial-

reports) ready for download.

corporate calendar

June 27, 2023 General Assembly

About Santhera

Santhera Pharmaceuticals (SIX: SANN) is a Swiss company

Specialty pharmaceutical company focused on the development and commercialization of

innovative medicines for rare neuromuscular and pulmonary diseases

with high medical needs. The company owns one

exclusive license for all indications worldwide for vamorolone

dissociative steroid with a novel mode of action, which in a

Pivotal study in patients with Duchenne muscular dystrophy (DMD).

alternative to standard corticosteroids. For vamorolone to

Santhera has FDA treatment for DMD

an application for approval (NDA) or at the European Medicines Agency (EMA)

a Marketing Authorization Application (MAA) under review and with the UK

Medicines and Healthcare products Regulatory Agency (MHRA)

submitted an MAA. The clinical pipeline also includes lonodelestat for

Treatment of cystic fibrosis (CF) and other neutrophils

lung diseases. Santhera has the rights to its first approved product,

Raxone® (idebenone), outside North America and France for the treatment of

Leber’s hereditary optic neuropathy (LHON) out-licensed to the Chiesi Group.

For more information, please visit www.santhera.com.

Raxone(®) is a trademark of Santhera Pharmaceuticals.

For more information please contact:

[email protected] (mailto:[email protected]) or

Eva Kalias, Head of Investor Relations & Communications

Phone: +41 79 875 27 80

[email protected] (mailto:[email protected])

Disclaimer / Forward-Looking Statements

This communication constitutes neither an offer nor an invitation to subscribe

or to purchase securities of Santhera Pharmaceuticals Holding AG.

This publication may contain certain forward-looking statements about the

Company and its operations included. Such statements are with

certain risks, uncertainties and other factors involved

can lead to actual results, financial condition, achievements

or achievements of the company differ materially from those which

expressed or implied in these statements. Readers should

therefore, do not place undue reliance on these statements, particularly

not in connection with contracts or investment decisions. The

Company disclaims any obligation to update these forward-looking statements

To update.

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