Understanding Tertiary Prevention in Multiple Sclerosis
Multiple sclerosis (MS) is a complex neurological condition that not only affects individuals on a physical level but also brings forth secondary and tertiary complications that can greatly diminish their quality of life. In this article, we delve into the concept of tertiary prevention, highlighting recent projects aimed at alleviating some of these pressing issues for those living with MS.
What is Tertiary Prevention?
Tertiary prevention refers to strategies aimed at preventing the progression of disease and mitigating complications after a diagnosis has been made. In the context of MS, primary symptoms—such as impaired motor function—can lead to various secondary complications, including falls, sleep disturbances, and urinary tract infections. These complications can significantly affect the psychosocial well-being and career prospects of individuals living with MS. As their disability progresses, these complications are likely to escalate, making effective tertiary prevention crucial.
The aim of tertiary prevention is to maintain the quality of life for those affected by MS by addressing and managing complications early. This can involve a range of approaches, including medical interventions, lifestyle changes, and community support initiatives.
Innovative Projects on Tertiary Prevention
In 2025, two key projects have been selected for DMSG funding that illustrate innovative approaches to tertiary prevention in MS. Each project brings forth a unique solution to help individuals manage the intricacies of living with MS.
Project 1: LUTiMS – Lower Urinary Tract Dysfunction in Multiple Sclerosis
A significant number of individuals with MS experience bladder dysfunction, impacting their daily lives and overall health. Research indicates that seven out of ten people with MS suffer from this issue. Despite existing treatment options, many do not utilize them effectively.
The LUTiMS project, led by Dr. Insa Schiffmann and Professor Christoph Heesen, aims to develop an online platform equipped with a chatbot. This platform will provide comprehensible information regarding bladder issues for those affected by MS.
The goal is to prompt early treatment interventions to alleviate discomfort and enhance the quality of life. During the initial test phase, 50 individuals with MS will gain access to this platform to evaluate its effectiveness and user-friendliness.
Project 2: High-Intensity Interval Training and Its Effects on MS Symptoms
Exercise has long been recognized for its myriad benefits, including improved physical fitness and mental well-being. In the context of MS, it may also play a role in reducing inflammation and psychological symptoms such as depression and anxiety.
This project, directed by Univ.-Professor Philipp Zimmer, investigates the effects of supervised high-intensity interval training over a 12-week period. The researchers aim to examine how this form of exercise may influence metabolic processes related to tryptophan—a key amino acid in the body—that are altered in individuals with MS.
The study will also explore the potential connections between exercise, mental health, and the metabolic changes that occur in individuals with MS, comparing results with a healthy control group.
Support and Funding for Tertiary Prevention Research
The success of these innovative projects is made possible through the financial backing from DMSG’s extensive network of private donors and partnerships with pharmaceutical companies, including Bristol-Myers Squibb, Neuraxpharm, and others. In total, both projects have secured approximately €225,000 in funding to conduct their research over the next two years.
Conclusion: A Hopeful Future for MS Research
The DMSG remains committed to supporting research initiatives that enhance the lives of people living with MS. As these projects unfold, results will be shared through the organization’s website and their magazine, Aktiv! The commitment of the DMSG and its partners underscores the importance of tertiary prevention in improving both health outcomes and the quality of life for those affected by multiple sclerosis. Through concerted efforts in research and community engagement, a brighter future for individuals living with MS is not just a hope, but a tangible reality.
